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Anode Acidic (low pH) O2 produced H2O – 2e- ↔ ½O2 + 2H+ Cathode Alkaline (high pH) H2O + e- ↔ ½H2 + OH- |
StimGen-SXT Technology |
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DC ablation, which is also known as
electrochemical therapy, has been studied at leading institutions worldwide
using external devices. The
reported mechanisms of DC ablation, which apply to external as well as
implantable devices, are as follows: ·
A strongly acidic region (low pH) is generated at the
positive electrodes (anode). Molecular oxygen and chlorine are also
generated. ·
A strongly alkaline region (high pH) is generated at the
negative electrodes (cathode). ·
Tumor cells die from the toxic pH extremes and the chlorine
in these precisely defined regions. ·
The dead cells are removed by the immune system. DC ablation has many potential advantages over
other ablative techniques such as radio frequency (whether done at low or
microwave frequencies), cryotherapy, percutaneous alcohol injection, and
percutaneous acetic acid injection.
These include: ·
Precise control over ablated region lowers risks ·
Quick implant (short OR time) followed by slow treatment. ·
Ability to treat multiple tumors simultaneously. ·
Ability to treat tumors with vascular involvement due to a
lack of the “heat sink” effect that limits thermal ablation
procedures. These comments have not
been reviewed by the FDA. |
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Copyright © 2005 OncoStim, Inc. |
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